Associate Principal Scientist Microbiology

Debiopharm is an independent biopharmaceutical company based in Switzerland with an ongoing commitment to research in oncology and bacterial infections in order to improving patient outcomes and quality of life. Our main activities include drug development, drug manufacturing and digital health investment. Debiopharm International SA aims to develop innovative therapies that target high unmet medical needs. Bridging the gap between disruptive discovery products and real-world patient reach, we identify high-potential compounds for in-licensing, clinically demonstrate their safety and efficacy and then select large pharmaceutical commercialization partners to maximize patient access globally.
Here:https://apply.workable.com/debiopharm-group-sa/

For our Translational Medicine, Pharmacology & Screening organization based at our Headquarters in Lausanne, we are looking for a

Associate Principal Scientist Microbiology

In this role, you will represent the Pharmacology & Screening (P&S) function in Translational Medicine team and participate in the development of new antibiotics to combat antibacterial resistance.

Your responsibilities will be but not limited to:
Represent the Pharmacology and Screening function in Clinical Study teams, Translational Medicine, and Global Project Teams:

• Design, plan, manage and report microbiology and pharmacology studies:

• In vitro/in vivo compounds selection and profiling, including off target characterization
• Proof of concept in vivo studies – PK/PD
• Mechanism of action and resistance studies

• Identify and lead method development/validation and analyses of clinical isolates and pharmacodynamic clinical biomarkers / Contributes to the development of ASTs in line with EUCAST and CLSI requirements
• Determine, implement, and manage the clinical microbiology analyses, data analyses and reporting according to GCPs and GCLPs
• Management of outsourcing activities to an international network of CROs
• Management of external collaborations with KOLs and universities
• Input the elaboration of the clinical development strategy
• Contribute to the preparation of the pharmacology and clinical documentation required for Health Authorities submissions
• Participate in external scientific communications and represent the organization during international scientific events
• Contribute to in/out licensing activities and internal innovation pipeline

• PhD in relevant in Microbiology
• 5-7 years experience in Translational Research and antibiotics R&D in industry, leading global projects to deliver Data packages
• Proven experience in overseeing external vendors and partners (contracts, budgets)
• In-depth knowledge in own discipline and broad knowledge of related disciplines within the function
• Knowledge of GCP and ICH guidelines; animal welfare regulations, and relevant regulatory guidelines (training can be done after recruitment)
• Excellent Communication skills in English
• You are a team player, looking to tackle challenges together with your team
• Experience in Oncology would be a plus

• An international and highly dynamic environment, with a long term vision.
• The opportunity to join a successful company, at the forefront of the most advanced scientific developments in the industry and be exposed to many areas within clinical development and the pharmaceutical industry.
• The possibility to be in a company in which innovation, people and entrepreneurship are the fundamentals of its success.

The use of external staffing agencies or recruiters requires prior approval from our Human Resources Department. The Human Resources Department at Debiopharm requests external staffing agencies or recruiters not to contact Debiopharm employees or members of the Board of Directors directly in an attempt to present candidates.
Submission of unsolicited resumes in advance of an agreement between the Human Resources Department and the external staffing agency or recruiter does not create any implied obligation on the part of Debiopharm.
Debiopharm will not accept unsolicited resumes from any source other than candidates themselves for either current or future positions.