Associate Principal Scientist Toxicology

Job content

Debiopharmis an independent biopharmaceutical company based in Switzerland with an ongoing commitment to research in oncology and bacterial infections in order to improving patient outcomes and quality of life. Our main activities include drug development, drug manufacturing and digital health investment. Debiopharm International SA aims to develop innovative therapies that target high unmet medical needs. Bridging the gap between disruptive discovery products and real-world patient reach, we identify high-potential compounds for in-licensing, clinically demonstrate their safety and efficacy and then select large pharmaceutical commercialization partners to maximize patient access globally.

Here: https://apply.workable.com/debiopharm-group-sa/

Debiopharm International S.A. identifies high-potential compounds for in-licensing, conducts clinical development and then selects large pharmaceutical commercialization partners to maximize patient accsess across the globe.

For our Translational Medicine Department based at our Headquarters in Lausanne, we are looking for a

Associate Principal Scientist Toxicology

The Toxicology team is dedicated to accelerating the development of new therapies for unmet medical needs by selecting the best safest drug candidates.

Your responsibilities will be but not limited to:

• Assess the non clinical safety profile of drug candidates (small molecules to complex biological products) from target assessment to registration and participate in early compound selection from
• Be a member of, closely collaborate and provide toxicological expertise to multidisciplinary teams
• Manage preclinical safety studies in Contract Research Organizations: design, monitor, discuss and report the safety findings;
• Contribute to the preparation of preclinical safety regulatory documents (including IDB, summaries for IND and IMPD, briefing documentation)
• Perform mechanistic studies on toxicology findings and identify toxicology biomarkers
• Work in matrix organization in close collaboration with other Translational Medicine functions (such as Pharmacology, DMPK, Personalized Medicine) and with clinical and regulatory functions to characterize the safety profile of our drug candidates:
• May represent the Translational Medicine position in global Team Projects;
• Participate in internal and external scientific communications (oral presentations, posters, publication).

Requirements:

• University degree in Life Science (PhD in relevant expertise area or equivalent in biomedicine)
• 5-8 years demonstrated experience in nonclinical toxicology in drug development (pharma industry, CRO, regulatory agency)
• Experience in oncology as an asset
• Ability to manage multiple projects across various development stages
• Knowledge in preclinical research, GCP and ICH guidelines and animal welfare regulations
• Scientific rigor and interest, curiosity, organizational skills
• Accustomed to work in a matrix organization with timeline-driven projects
• Excellent communication and presentation skills (oral and written)
• Project management experience as an asset
• Fluent in English
• Good IT and analytical skills

Benefits:

• An international and highly dynamic environment, with a long term vision.
• The opportunity to join a successful company, at the forefront of the most advanced scientific developments in the industry and be exposed to many areas within clinical development and the pharmaceutical industry.
• The possibility to be in a company in which innovation, people and entrepreneurship are the fundamentals of its success.

The use of external staffing agencies or recruiters requires prior approval from our Human Resources Department. The Human Resources Department at Debiopharm requests external staffing agencies or recruiters not to contact Debiopharm employees or members of the Board of Directors directly in an attempt to present candidates.

Submission of unsolicited resumes in advance of an agreement between the Human Resources Department and the external staffing agency or recruiter does not create any implied obligation on the part of Debiopharm.

Debiopharm will not accept unsolicited resumes from any source other than candidates themselves for either current or future positions.