In Vitro Pharmacology Technician

Genkyotex S.A

View: 146

Update day: 21-03-2024

Location: Plan-les-Ouates Genève GE

Category: Other

Industry:

Job type: Full-time

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Job content

About us

Calliditas Therapeutics is a specialty pharmaceutical company based in Stockholm, Sweden focused on identifying, developing and commercializing novel treatments in orphan indications, with an initial focus on renal and hepatic diseases with significant unmet medical needs.

Genkyotex is a subsidiary company of Calliditas Group, Sweden. Genkyotex activities focus on the characterization of novel NOX enzyme inhibitors in various in vivo disease models to support the identification of novel drug candidates in chronic inflammatory and fibrotic diseases. Our lead candidate, Setanaxib, is under clinical evaluation for Primary Biliary Cholangitis.

Position summary

To strengthen the In vitro-pharmacology unit, we are looking for a highly motivated Technician. The successful candidate will perform in vitro screening assays and development to support our drug discovery research programs. Under the supervision of the Head of In vitro Pharmacology, In vitro Pharmacology technician will participate to the development of novel in vitro assays and will evaluate all chemical compounds synthetized in the battery of screening biochemical and cellular assays available. The permanent position required use of robotics pipettors, various readout technologies and protein and cellular (including primary) expertise.

Key tasks and responsibilities

  • Run biochemical and cell-based assays using liquid handler workstation and microplate readers in accordance with established protocols and procedures
  • Analyze, interpret and record all experimental data accurately in the specified format (written and/or electronic.), with efficient transfer to the head of in vitro pharmacology
  • Participate to development of in vitro assays (biochemical and cell), optimize current assays when relevant
  • Manage the stock of the compounds and the compound libraries
  • Maintain stable cell lines with large scale amplification of adherent cells for screening assays and production of cellular membranes
  • Responsible for the cell bank management
  • Produce membranes and recombinant proteins. Perform quality controls and keep tracking of the biological stocks
  • Maintain a functional laboratory (equipment record books, preventive maintenance of instruments, troubleshooting and resolving problems)
  • Perform inventory, stocking and ordering of consumable supplies

Education and experience requirements

  • Apprenticeship as Biology Lab Technician (“Laborantin CFC” or Bachelor or equivalent)
  • Experience with cell biology techniques, cell and bacterial culture
  • Able to work independently and as a team player
  • Dynamic, well-organized and detail-oriented person that respects the deadlines
  • Computer literacy (MS Office)
  • Knowledge of scientific English
  • Experience of 1-2 years in a biotech/pharmaceutical industry will be an advantage
  • Swiss work permit or EU citizen preferred
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Deadline: 05-05-2024

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