Senior Scientist I/II, Oncology Translational Research

☞ Novartis

View: 201

Update day: 21-03-2024

Location: Basel Basel-Stadt BS

Category: R & D Science Labor Other

Industry: Pharmaceutical Manufacturing

Position: Associate

Job type: Full-time

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Job content

Job Description

Oncology Translational Research at Novartis Institutes for Biomedical Research is recruiting an independent scientist with a strong background in cellular and molecular biology to join the Oncology Pathology and Biomarkers group in Basel, Switzerland.

We are seeking a highly motivated scientist with at least 3 years of experience in pre-clinical/translational research within the pharmaceutical industry or in an academic laboratory. You will be responsible for the generation of novel, high quality data to progress research programs to the clinical trial stage. By using a variety of molecular and cell biology approaches you will design, perform, and analyze studies using human tissues, xenograft models and cell lines, applying techniques like immunofluorescence microscopy, qPCR, western blotting, and other cutting-edge technologies. Your work will contribute to the identification of molecular predictors of response to cancer drugs and resistance, and to the discovery of potential combination therapies. While closely interacting with your lab head and colleagues in the group, you will be expected to flexibly contribute to local and global projects as needed and to proactively share knowhow and experience across groups.

Major accountabilities include:
  • Independently design and perform experiments with a high degree of complexity, demonstrating expertise in a wide range of techniques (e.g., IF, cell culture, immunoblotting, qPCR).
  • Understand role of biomarkers in FIH studies and assay validation process, support development of biomarker assays to implement in the clinic internally and externally.
  • Be a self-starter and independently seek out opportunities to learn and contribute within Oncology and the larger NIBR organization.
  • Work collaboratively with others in the group and project team members. Communicate directly with project teams to design and execute experiments, and subsequently present and discuss results.
  • Recognize problems and troubleshoot.
  • Represent the lab at project team meetings.
  • Contribute to report writing and other publications.
  • Actively participate in supporting, teaching, and learning from colleagues in the Oncology Pathology and Biomarkers group.
  • Fully understand and participate in the drug development process, including reaching out to and working with early discovery and late development teams for project specific questions.
  • Contribute to the efficient management of a functional laboratory, including maintenance of technical equipment and compliance with human tissue guidelines.
Commitment to Diversity & Inclusion:

Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

Minimum Requirements
  • MSc or BSc or qualified Lab Technician (apprenticeship/vocational training) in Cellular Biology, Molecular Biology, or other relevant discipline
  • Advanced/Fluent English oral and written
  • 3 years of practical work experience in biomedical research in industry or academic laboratory
  • Proficiency and hands-on experience in applying a wide range of cellular and molecular biological methods, such as qRT-PCR, cloning, CRISPR, cell culture, cell viability assays, transient/stable cell line generation, immunoblotting, and ELISA
  • Basic experience using basic bioinformatics tools to support experimental design, data analysis and interpretation is considered a plus
  • Knowledge of cancer signaling/biology is additionally preferred
  • Experience working successfully within a high productivity and quality environment
  • Proven ability to effectively collaborate in an interdisciplinary team environment
  • Highly collaborative and self-motivated team player
  • Excellent organizational and communication skills
Why Novartis?

767 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.

We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what’s possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!

Imagine what you could do here at Novartis!

Division

NIBR

Business Unit

Oncology NIBR

Country

Switzerland

Work Location

Basel

Company/Legal Entity

Novartis Pharma AG

Functional Area

Research & Development

Job Type

Full Time

Employment Type

Regular

Shift Work

No

Early Talent

No
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Deadline: 05-05-2024

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