Senior Manager, MS&T API

Contenuto del lavoro

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

The Role

Bristol Myers Squibb is looking to recruit a permanent Senior Manager, MS&T APIto join our Pharma Manufacturing Science and Technology group. The role will be based in Dublin (Ireland) or Boudry (Switzerland). The Pharma Manufacturing Science and Technology group is responsible for the provision of technical expertise in the areas of API and Drug Product manufacture in an external manufacturing environment.

This Senior Manager, MS&T API role requires demonstrated experience of the technical management of processes relating to the manufacture of small molecule API.

Key Duties And Responsibilities

• Technical leadership and oversight for the manufacture of a portfolio of products (APIs, Intermediates and Starting Materials) produced at Contract Manufacturing Organisations (CMOs) for Bristol Myers Squibb.
• Ensuring robust process performance at our CMOs. Providing technical leadership for process monitoring, control and continuous improvement strategies.
• Leadership and accountability for technology transfers.
• Providing technical leadership in the understanding of root causes for manufacturing process deviations.
• Providing technical leadership for change management, investigation CAPA identification and related activities at CMO site.
• Driving strategies to improve processing efficiency and to ensure optimised technical support for manufacturing, technology transfer and process scale-up.
• Supporting CMO/vendor selection – preparation of technical information packages, leading technical due diligence and site assessments, technical evaluation of RFIs and RFPs.
  

Qualifications, Knowledge And Skills Required

• A graduate or post-graduate level qualification in chemistry, chemical engineering or related field with an extensive relevant experience.
• Recognised technical leader and subject matter expert in API process development and commercial manufacture.
• Demonstrated proficiency in project management and technical leadership capability.
• Solid experience in commercial manufacturing of API in accordance with GMP standards in an external manufacturing environment.
• Advanced knowledge and understanding of process, engineering, analytical and regulatory requirements (cGMP, filing, EHS).
• Demonstrated capability to lead complex technical investigations.
• Thorough understanding of statistical process analysis and control methods.
• Confident management of internal and external stakeholder relationships.
• Highly proficient in technical writing and technical presentations.
• Excellent communication and negotiation skills as well as the ability to translate technical issues into business impact and relevant solutions.
• The position will require varying levels of travel - estimated at 20%.
  
What’s Important To Us

Employees are expected to display the BMS Values, which move us toward our mission to discover, develop and deliver innovative medicines that help patients prevail over serious diseases

• Passion Our dedication to learning and excellence helps us to deliver exceptional results.
• Innovation We pursue disruptive and bold solutions for patients.
• Urgency We move together with speed and quality because patients are waiting.
• Accountability We all own BMS’ success and strive to be transparent and deliver on our commitments.
• Integrity We demonstrate ethics, integrity and quality in everything we do for patients, customers and colleagues.
• Inclusion We embrace diversity and foster an environment where we can all work together at our full potential.
  
We have a passion for tackling the toughest diseases, which inspires innovation and speed in our daily work and a sense of accountability to the patients we serve.

Why you should apply

• You will help patients in their fight against serious diseases
• You will be part of a company that encourages excellence and innovation, respects diversity, develops leaders and values its employees.You’ll get a competitive salary and a great benefits package
  
Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.