Principal Scientist - in vivo Pharmacology/Immunology (80-100%*)

仕事内容

About The Role

Location: Full time, onsite, Basel, Switzerland #onsite

Job Purpose:

We are looking for a Principal Scientist level candidate to lead a lab in the in vivo Pharmacology group within the Immunology (IMM) Department. The successful candidate will have a Ph.D. and postdoctoral training in immunology and extensive experience working with mouse models to support drug discovery for treatment of immunologic and inflammatory diseases. The successful candidate is passionate for approaches to identify and validate novel targets using state-of-the art technologies.

Responsibilities:

The Lab Head will contribute to a strong and sustainable Immunology portfolio by:

• Driving and supporting the identification of novel targets in collaboration with interdisciplinary project teams and disease focus groups (e.g. for joint inflammation)
• Designing and implementing in vivo and in vitro studies to test the potency and selectivity of drug candidates in close interaction with chemistry teams
• Elucidating the molecular mode of action of drugs in context of drug discovery projects
• Investigating and developing in vitro/in vivo methods or technologies for the rapid advancement of drug discovery projects towards the clinic
  
  

The candidate will collaborate with an interdisciplinary group of immunology scientists and associates to provide expert biology support to preclinical and clinical drug development projects for novel therapeutic agents. Commensurate with experience, the candidate will also provide biology expertise to late-stage clinical projects in a cross-functional setting.

Commitment to Diversity & Inclusion:

We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

Role Requirements

What you will bring to the role:

• Ph.D. and 3-5 years of postdoctoral experience in immunology with a strong publication record
• Expert understanding of in vivo disease models and experience in performing mechanistic studies in animal models of autoimmune and inflammatory diseases is required
• Good understanding of state-of-the art methods to investigate cellular and molecular drivers of complex autoimmune and inflammatory diseases, such as psoriatic arthritis, lupus erythematosus, Sjögren`s disease and others
• Profound understanding of pharmacological principles (e.g. target engagement) and experience in developing pharmacology assays for compound characterization are preferred
• Curiosity, strong analytical and organizational skills and ability to work in interdisciplinary teams
• Excellent oral and written communication and presentation skills in English
• Restrictions on flexible working options may apply and will be discussed during interview if applicable.
  
  

Why Novartis:

Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our

people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more he re: https://www.novartis.com/about/strategy/people and culture

You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits rewards

Commitment to Diversity and Inclusion:

Novartis is committed to building an outstanding, inclusive work environment and diverse teams’ representative of the patients and communities we serve.

Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network

Accessibility and accommodation

Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Division

Novartis Institutes for BioMedical Research

Business Unit

IMMUNOLOGY - NIBR

Work Location

Basel

Company/Legal Entity

Novartis Pharma AG

Functional Area

Research & Development

Job Type

Full Time

Employment Type

Regular

Shift Work

No

Early Talent

No