Associate Director, Raw Material Supply Chain

Conteúdo do emprego

Company Profile:

Vaxcyte, Inc. (Nasdaq: PCVX) is a vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases. The Company is developing broad-spectrum conjugate and novel protein vaccines to prevent or treat bacterial infectious diseases. Vaxcyte’s lead candidate, VAX-24, is a 24-valent, broad-spectrum, carrier-sparing pneumococcal conjugate vaccine (PCV) being developed for the prevention of inva s ive pneumococcal disease (IPD). The Company is re-engineering the way highly complex immunizations are made through modern synthetic techniques, including advanced chemistry and our exclusively licensed XpressCFTM cell-free protein synthesis platform. Unlike conventional cell-based approaches, the Company’s system for producing difficult-to-make proteins and antigens is intended to accelerate its ability to efficiently create and deliver high-fidelity vaccines with enhanced immunological benefits. Vaxcyte’s pipeline also includes VAX-31, a 31-valent PCV candidate; VAX-A1, a prophylactic vaccine candidate designed to prevent Group A Strep infections; VAX-PG, a therapeutic vaccine candidate designed to slow or stop the progression of periodontal disease; and VAX-GI, a vaccine program designed to prevent Shigella. The Company is driven to eradicate or treat invasive bacterial infections, which have serious and costly health consequences when left unchecked. For more information, visit www.vaxcyte.com .

Vaxcyte, headquartered in San Carlos, CA, went public in June 2020 and currently has a team of approximately 180 employees and anticipates continued, significant growth. Following equity offerings in October 2022 and April 2023, which generated over $1.1 billion in net proceeds, the Company’s balance sheet is further strengthened to advance its pipeline of novel vaccines, including VAX-24. These financings followed positive data readouts from Vaxcyte’s Phase 1/2 proof-of-concept study evaluating VAX-24 in adults aged 18-64 and Phase 2 study in adults 65 and older. The Company believes these results support a best-in-class potential for VAX-24, which was designed to replace the current standard-of-care in adults and children. VAX-24 is being investigated for the prevention of IPD, which can be most serious for infants, young children, older adults and those with immune deficiencies or certain chronic health conditions. Given the global impact of pneumococcal disease remains significant, the public health community continues to advocate for vaccines that can offer broader protection to prevent IPD. Vaxcyte’s PCV franchise, consisting of VAX-24 and VAX-31, is designed specifically to address this need and has the potential to deliver the broadest protection for this very serious disease. We believe that our PCVs could receive regulatory approval based on successful completion of clinical studies utilizing well-defined surrogate immune endpoints, consistent with how other PCVs have obtained regulatory approval in the past, rather than requiring clinical field efficacy studies.

Summary:

This role has overall responsibility to support the raw material suppliers for commercial production of Vaxcyte PCV products. Responsibilities include:

• Enabling the raw material supplier setup and management for large scale CDMO commercial production. This will include establishing contracts and leading the operational planning for supplier enablement.
• Establishing and maintaining relationship with identified suppliers including supplier performance management.
  
  

This will be a remote position based in Switzerland. Candidates must be comfortable traveling to different sites within the country.

Essential Functions:

• Drive the operational implementation of raw materials procurement for large scale production plans, including delineating organizational roles and responsibilities, coordinating with relevant functions to outline material flows, contract and supplier management including CDMO resource management and systems integration.
• Report on supplier enablement for large scale commercial production progress.
• Transfer or establish contracts with all raw material suppliers for commercial production. Maintain contracts once established.
• Coordinate with Supplier Quality to establish Quality Agreements, as needed.
• Coordinate with finance and supply chain to enable supplier setup, forecasting and ordering.
• Coordinate with finance, IT and supply chain to define and drive the material and information flow and enable goods movement, goods receipt, forecasted inventory, consumption tracking and physical inventory count for raw materials,
• Coordinate with finance for supplier payment.
• Monitor, report and drive supplier performance (e.g. project goals, product on time delivery, yield, quality, etc).
• Coordinate and facilitate periodic business reviews / Joint Steering Committee meetings between Vaxcyte senior leadership and relevant counterparts at the Supplier.
• Monitor supplier’s overall health including financial position, strategy, ownership structure, leadership strength and investment plans and identify potential risks that could impact Vaxcyte.
  
  

Requirements:

• B.S. / B.A. degree or Advanced Degree (preferred).
• 10+ years’ experience working in sourcing and supplier engagement and strong supplier relationship management skills.
• Experience in biotech/pharmaceuticals supply chain/manufacturing a plus.
• Strong experience negotiating agreements.
• Strong experience leading cross-functional teams.
• Excellent communication skills. English fluency required and additional fluency in German preferred.
• All Vaxcyte employees require vaccination against COVID-19.
  
  

Reports to: Senior Director, Supply Chain Strategy & Sourcing (initial), GM Vaxcyte Switzerland (long term)

Location: Switzerland

Compensation:

The compensation package will be competitive and includes comprehensive benefits and an equity component.

Send resumes to:

careers@vaxcyte.com

Vaxcyte, Inc.

825 Industrial Road, Suite 300

San Carlos, CA 94070

We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.