Discovery Scientist in RNA metabolism in Neurodegeneration (m/f/d)

☞ Roche

View: 149

Update day: 08-04-2024

Location: Basel Basel-Stadt BS

Category: R & D Science Labor High Technology Mechanical / Technical Electrical / Electronics

Industry: Medical Equipment Manufacturing Biotechnology Research Pharmaceutical Manufacturing

Position: Associate

Job type: Full-time

Loading ...

Job content

The PositionIn Roche’s Pharmaceutical Research and Early Development organization (pRED ), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed. The position is located within the Exploratory Neuroscience Section in the Neuroscience and Rare Disease (NRD) Discovery team at Roche in Basel.Job MissionIn multiple neural diseases including amyotrophic lateral sclerosis (ALS), as well frontotemporal dementia (FTD) and common diseases such as Alzheimer’s, RNA processing has major impact on neurodegenerative diseases. We are looking for a highly motivated Discovery Scientist to focus on studying disease RNA processing and the roles that RNA binding proteins play in disease. The position is aimed to increase expertise and research towards RNA biology and neurodegeneration including modeling RNA-binding protein dynamics (RBP), splicing, and linking to cell functions associated with neurodegeneration (eg. axonal degeneration, hyper excitability) by developing novel cellular models. The scientist will collaborate with multidisciplinary project teams focused on therapeutics and will work with research associates.Your Profile
  • PhD or MD/PhD in neuroscience, cellular biology and biochemistry
  • Expertise in RNA biochemistry including studying RNA-protein interactions and splicing
  • Expertise in iPSC technology, and CRISPR genome editing to develop, utilize and characterize hPSC disease models
  • Experience with advanced in vitro-culture techniques using other cell types
  • Proven scientific-track record through impactful publications in relevant fields including RNA biology in both PhD and postdoc
Who we areAt Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.Roche is an Equal Opportunity Employer.
Loading ...
Loading ...

Deadline: 23-05-2024

Click to apply for free candidate

Apply

Report job
Loading ...
Loading ...

SIMILAR JOBS

Loading ...
Loading ...