Scientist, Investigative and Immunosafety, pRED Pharmaceutical Sciences

Job content

The PositionIn Roche’s Pharmaceutical Research and Early Development organisation pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.Pharmaceutical Sciences (PS) is a global function which covers several research areas including Immunosafety and Investigative Safety (I2S). In I2S, we help bring the best medicine to patients using innovative safety science. We are inspired to provide a transparent roadmap of preclinical safety assessment, balancing our safety findings against efficacy considerations. We use advanced, science-based models, back-translating from the clinic to generate forward-translatable, human-relevant safety strategies.Job MissionAs an experienced in vitro model scientist in the Department of Pharmaceutical Sciences, you will focus on the qualification of in vitro models with an emphasis on teratogenicity and reproductive toxicology assessment.As part of the Investigative Safety and Immunosafety group, you will work in close collaboration with scientists from different departments within PS/pRED including Nonclinical Safety and the Institute of Human Biology (IHB) to generate and integrate molecular, cellular, tissue and functional data with the goal of delivering unique and holistic insights into drug safety and enable informed decisions to bring the best drugs to patients.Your ImpactIn this position:

• You will be responsible for set-up, applying and validating in vitro models for safety assessment specifically in the area of developmental and reproductive toxicology.
• You will perform and guide related wet lab activities.
• In addition, you will contribute and, based on experience gained, be ultimately responsible for our in-house in vitro DART strategy in close collaboration with your stakeholders in pharmaceutical sciences.

Your ProfileYou have a postgraduate scientific degree in the field of developmental biology, pharmacology or cell biology with a strong focus on in vitro model development.We are looking for a highly motivated, experienced scientist with the following expertise:

• Background on in vitro model development and application and strong skills in the wet lab.
• Expertise in vitro models evaluation and qualification, as well as solid experience in applying this knowledge to answer complex biological questions
• Knowledge of developmental and reproductive toxicology is an asset
• Excellent interpersonal and communication skills and strong attitude to teamwork
• Excellent strategic thinking, self-initiative and a strong sense of accountability
• Ability and willingness to challenge, be challenged and learn
• Proficient in spoken and written English

Our commitmentRoche commits to recognising talent and aptitude. We prioritize encouraging and supporting our employees in their personal journeys by providing a safe, creative space to help them reflect, make decisions and grow in their career.We are confident that we find the most innovative solutions by gaining different perspectives, asking and answering hard questions, and challenging the status quo.Roche embraces diversity and equal opportunity in a serious yet enthusiastic way; we are devoted to building a team that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.Who we areAt Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.Roche is an Equal Opportunity Employer.