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Scientist, Molecular Immunology
View: 155
Update day: 25-04-2024
Location: Basel Basel-Stadt BS
Category: Other
Industry: Biotechnology Research
Position: Associate
Job type: Full-time
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Job content
Matterhorn Biosciences is looking for aScientist in Molecular Immunology.Matterhorn Biosciences is a preclinical stage biotechnology company pioneering the discovery and development of novel T cell therapy for cancer treatment. We are an exciting, motivated group of scientists who are determined to make a difference for modern human medicine.
As we continue to build the R&D team, we are seeking to appoint a Scientistto support activities in TCR Discovery. The role will require the precise application of a diverse range of laboratory-based skills, especially in molecular biology. As such, the successful candidate will have significant research experience and be highly motivated, enthusiastic with a positive “can do” attitude, hands-on, strong organizational skills, and able to work independently.
Responsibilities
You will further strengthen our team by contributing to the development of Matterhorn Biosciences. You will form a key part of the TCR Discovery program, building the infrastructure to sequence and clone novel MR1-specific TCRs and help propel our company forward. Your role will be comprised of:
- Independent design and execution of experiments related to next-generation sequencing of primary human T cells, cloning and functional expression of candidate TCRs for screening
- Establishing systems for automation and increasing throughput for sequencing, cloning and testing candidate TCRs in functional assays
- Supervision and training of research associates
- Independent analysis and presentation of experimental results
- Supporting management for the preparation of slide decks
- Keeping abreast of relevant literature and providing regular updates to the wider team
Qualifications
You have significant laboratory experience, along with a detailed understanding of the cutting-edge approaches used in a molecular and cellular immunology laboratory. Specifically, we are looking for candidates with the following:
- PhD, or university degree with 0-3 years of industry experience in a related field, or Master’s degree with 5+ years of relevant experience
- Experience in developing and applying next-generation sequencing in a related field
- In-depth knowledge of T cell biology and cancer immunotherapy
- Experience with transfection and/or transduction of primary immune cells
- Proficient at a range of molecular & cell biology techniques including but not limited to PCR, flow-cytometry, cell sorting, and ELISA
- Experience with automated high-throughput systems is a plus
- Know-how in experimental design and ability to work independently
- Able to work in a highly flexible environment
- Able to communicate with team members and cross-functional project teams
- Good English communication skills, both oral and written
- Offices: Our well-equipped laboratories and offices are located at the Tech Park Basel, a premier address for early-stage start-ups.
- Commuter Benefits: We support our employees tailored to their personal needs in commuting to work and offer parking facilities or a commuter contribution.
- Flexible Working: We support flexible working as appropriate.
- Christmas Closure: In addition to the 24 holidays per year, our offices/labs are closed between Christmas and New Year.
- Birthday Retreat: On top of that, your birthday is your personal holiday - our employees enjoy their birthday with a day off.
- Food: We like get-togethers during lunch time. Enjoy tasty, subsidised meals from our FELFEL food fridge.
- Coffee: Meet up with your colleagues and grab free coffee.
- Development: We support the individual development of our employees.
- German Lessons: For our international employees we support German lessons to speed up integration.
- Creativity: We offer an innovative and creative environment.
- People: We are an international and diverse team with talented and passionate people.
- Fun: From time-to-time we organise cool off-site summer and winter team events.
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Deadline: 09-06-2024
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