Principal/ Senior Principal Pharmacometrician* (80-100%**)

Job content

Job Description

Do you want to be at the forefront of the fight against multiple diseases, make an impactful contribution by bringing transformative therapies to patients and be part of Novartis’ mission to reimagine medicine to improve and extend people’s lives?

The Pharmacometrics community at Novartis comprises a group of about 80 quantitative scientists supporting a portfolio of more than 80 clinical development projects in 10 therapeutic areas every day.

Quantitative sciences are a critical part of bringing these new medicines to patients. Pharmacometrics Scientists bring innovative modeling and simulation skills to every aspect of clinical drug development over a wide range of disease areas and drug modalities. We are dedicated to creating a collaborative and supportive culture where teamwork and learning is emphasized and innovative problem solving is encouraged.

Come and join an industry leader where you will have the opportunity to grow and contribute as a quantitative drug development scientist in early- and late-stage projects.

The Senior Principal / Principal Pharmacometrics Scientist leads the planning, execution, and delivery of Pharmacometrics strategy on clinical projects within (early/full) clinical development. In this role, you will be responsible for the discussion and implementation of Pharmacometrics methodologies that successfully address the Novartis Institutes for Biomedical Research (NIBR) and Global Drug Development (GDD) objectives on the assigned projects.

You will provide Pharmacometrics support for regulatory submissions and supply to drug development decisions with internal and external partners and work with experienced pharmacometricians to collaborate with cross-functional international teams to develop quantitative strategies and will also have the opportunity to explore innovative pharmacometrics methodologies that optimally address the research and development objectives.

Your responsibilities include, but are not limited to:

• Providing exploratory data and modeling analyses for clinical projects
• Contextualizing the modeling question with the relevance to drug and disease biology
• Developing an understanding of drug development applied to scoping relevant questions for Pharmacometrics analysis
• Helping colleagues with review and validation of programs and outputs
• Communication of modeling to project teams in multiple settings such as decision board meetings, small sub-teams, etc.
• Training in good clinical practice for data handling and analysis
• Learning and developing new quantitative analysis methods and application to practical situations in drug development
• Developing posters, publications, presentations for internal and external conferences
  

Commitment to Diversity & Inclusion:

Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

Minimum Requirements

What you’ll bring to the role:

• Ph.D. in Pharmacology, Biology, Engineering, Mathematics, Statistics, or a field with significant modeling-related content (or equivalent) with 2+ years modeling related activity in mathematical /statistical modeling with strong working knowledge / experience with R / MATLAB / NONMEM / Monolix. Prior pharmacometric experience is not required. *We will hire at Principal or Senior Principal level depending on the experience of the successful candidate.
• Proven ability for innovative problem solving, strong fundamentals in mathematical modeling, collaboration skills across functional areas and good communication skills to both quantitative and non -quantitative scientists.
• We will hire at Principal or Senior Principal level pending on the experience of the successful candidate.
• Some restrictions to flexible working models may apply and will be discussed at interview if applicable
  

Why Novartis?

766 million lives were touched by Novartis medicines in 2020, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives. We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working. We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what’s possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!

Imagine what you could do here at Novartis!

Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network

Division

Global Drug Development

Business Unit

CD&A GDD

Country

Switzerland

Work Location

Basel

Company/Legal Entity

Novartis Pharma AG

Alternative Country 1

USA

Functional Area

Research & Development

Job Type

Full Time

Employment Type

Regular

Shift Work

No

Early Talent

Yes