Technical Project Lead - Protein Engineering (100%)

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Technical Project Lead – Protein Engineering and Drug Development (100%)

Founded in 2004 by a group of PhD students as a spin-off from the University of Zurich, Molecular Partners AG is a thriving and steadily growing clinical stage biotech company located in Zurich-Schlieren (Switzerland) with 200 highly qualified employees.

In order to advance modern medicine and significantly improve the management of serious diseases, we have developed and successfully established a powerful new class of potent, specific and versatile small protein therapies, called DARPin therapeutics.

The continuous development of a broad portfolio of therapeutic product candidates in oncology, virology and ophthalmology based on the company’s proprietary DARPin platform allowed a successful listing of the company on the SIX Swiss Exchange and Nasdaq (ticker: MOLN). Next to our own pipeline of drug candidates we have entered into collaborations with leading international pharmaceutical companies, including AbbVie, Amgen and Novartis.

The highly dedicated, multi-disciplined team at MP is committed to developing breakthrough medicines for serious diseases.

As an addition to our skilled Lead Generation team, we are looking for a highly experienced Technical Project Leader, responsible for the generation of therapeutic DARPins, from project initiation (target expression) to IND ready candidate.

This challenging and diverse position will include the following tasks and responsibilities:

• Deliver IND-ready therapeutic DARPin candidates within planned timelines;
• Strategic project plan, map critical decision points and drive the project to go-No go;
• Build and maintain all knowledge in support to the project and be the reference person for technical questions;
• Execution of the plan by (i) engaging, coordinating, managing the right matrix functions at the right moment; (ii) designing and setting up of meaningful experiments for all DARPin generation steps; (iii) ensuring data quality to enable decision-making;
• Participate to lab-work when needed and valuable to accelerate project progress;
• Take decision on the project and propose/endorse one solution over others in discussion with project team, LGLST and/or PRC;
• Keep the project team engaged and up to date;
• Ensure project documentation by internal ELN and other tools, keeping real time track of the project history/status.

For this challenging position, we are looking for a highly motivated individual, preferably with a Ph.D. in protein engineering or a related discipline, with 8+ years of industrial experience in protein-based drug development.

You should bring along:

• Strong background in protein binder generation and deep understanding of all steps of preclinical protein-based drug development;
• 8+ years’ experience in protein engineering and the generation of therapeutic proteins;
• PhD in Protein Engineering or related discipline;
• Profound experience in pre-clinical development and screening of target proteins;
• Deep passion and inner drive to generate therapeutic proteins;
• Critical, strategic, and tactical thinking to reach project value inflection points within agreed timelines;
• Clear scientific writing ability;
• Strong to-the-point communication skills that are adjusted to the audience;
• Experience working in a matrix-environment and interact and coordinate with different stakeholders;
• Ability to integrate relevant input from stakeholders;
• Efficient and straight-to-the-point communication/presentation, enabling stakeholders to understand the challenges/status of the project and to endorse a decisions;
• Ability to build trustful working relationships and to keep the project team motivation;
• Ability to perform, manage and navigate the project under pressure.

Partnership and collaboration are at the core of our company, our research activities and our product candidates. Molecular Partners offers an international working environment and the opportunity to collaborate with outstanding individuals from numerous disciplines, who contribute to our shared goals of scientific excellence, respectful teamwork and personal aspiration. We foster true innovation and creative thinking to advance our therapeutic product candidates and continue to be inspired by the difference we can make for our patients. At Molecular Partners you will discover a challenging job, inspiring colleagues and a true purpose. If you are interested in working at Molecular Partners, we are looking forward to hearing from you! Please submit your detailed curriculum vitae via our career portal.

We only accept online applications.

Please note Molecular Partners AG operates a list of preferred recruitment partners. For those partners who have no valid, signed agreement in place with Molecular Partners AG, all unsolicited resumes, CVs, anonymous profiles, or any other candidate details submitted through our website or to personal e-mail accounts of employees of Molecular Partners AG (including any of its subsidiaries, affiliates or related companies) are not subject to payment of any form of introduction, placement or referral fees.

Molecular Partners AG, Wagistrasse 14, CH-8952 Zurich-Schlieren, Switzerland.

www.molecularpartners.com